This page provides links to Sorting Intolerant From Tolerant (SIFT) and Variant Effect Predictor (VEP) to predict whether an amino acid substitution affects protein function.
SIFT missense predictions for genomes: Nature Protocols 2016; 11:1-9
. The Ensembl Variant Effect Predictor: Genome Biology Jun 6;17(1):122. (2016) doi:10.1186/s13059-016-0974-4
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In 2009 the Toronto International Data Release Workshop agreed on a policy statement about prepublication data sharing.
Accordingly, the data producers are making many of the datasets in T3 available prior to publication of a global analysis.
Guidelines for appropriate sharing of these data are given in the excerpt from the Toronto Statement.
I agree to the Data Usage Policy as specified in Toronto Statement.